The Cell and Gene Therapy group at King’s (CGT-K) manufactures a variety of Advanced Therapy Medicinal Products (ATMPs) in state-of-the-art Good Manufacturing Practice (GMP) facilities for novel therapies of different cancers and rare diseases.  

This post supports the translation of cutting-edge medicinal research into clinical application.

It is an opportunity to work within a leading translational Gene Therapy Innovation Hub led by the Centre for Gene Therapy and Regenerative Medicine, focussed on the delivery of Lentiviral and Retroviral gene therapy products for early phase clinical trials as well as AAV gene therapies. 

 

As an experienced scientist the post holder will work within the CGT-K MSAT team at Guy’s campus, involved in manufacturing cell therapies/ viral vectors for clinical trials. The MSAT team are responsible for engineering runs, preGMP productions, process optimisation and improvement and investigations in the MSAT labs. They will also take part in GMP productions as trainers and observers in the GMP cleanrooms. The post holder will learn a wide range of molecular and cell biology skills such as cell culture, transfections, QPCR, flow cytometry etc. They will also need to understand the demands of GMP manufacturing, including cleanroom operations, following and writing GMP compliant documentation such as SOPs and BMRs, change controls and operating inside a QMS. This is a cross functional role, and the post holder will need strong flexibility, interpersonal and organisational skills as they will be interacting with the Production, QA, QC and Technical teams, whilst ultimately reporting to the Head of MSAT.

 

This is a full time (35 hours per week), and you will be offered an indefinite  contract

 

 

 

To be successful in this role, we are looking for candidates to have the following skills and experience:

 

1.      Level 6 qualification, e.g. relevant undergraduate degree (Biological Sciences) or equivalent, plus work experience in relevant technical/scientific service posts

2.      Knowledge of GMP regulations

3.      Experience in cell and molecular biology relevant to recombinant vector manufacture

4.      Excellent spoken and written communication skills, with advanced computer use and strong interpersonal and influencing/behavioural skills to build a strong network to support the delivery of the service

5.      Ability to work independently based on an agreed work plan, setting own priorities and those of the team, working cooperatively to achieve the service objectives

6.      Comprehensive knowledge of regulations and best practice governing area of work, including Health & Safety and environmental sustainability.

 

1.       Working knowledge and experience in viral vector manufacture

2.      Experienced in process development

 

Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the page. This document will provide information of what criteria will be assessed at each stage of the recruitment process.

 

 

At King’s, we believe that the diversity of our community and a culture that is welcoming, open, inclusive and collaborative, are great strengths of the university.

 

The Equality Act of 2010 protects the rights of our students and staff and provides a framework to fulfil our duties to eliminate unlawful discrimination, harassment and victimisation and in addition, to advance equality of opportunity and foster good relations between those who share a protected characteristic and those who do not. At times, this will include balancing rights and beliefs that can feel in tension.

 

We are committed to free speech and to academic freedom, believing that our foundational purpose as a university, is to create spaces where a wide range of ideas, including ideas that are controversial, can be discussed and debated, and where members of our community can express lawful views without fear of intimidation, harassment or discrimination.

 

When engaging in the robust exchange of ideas, we ask that our community is mindful of our Dignity at King’s guidance.

 

We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the person specification section of the job description. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.

 

To find out how our managers will review your application, please take a look at our ‘How we Recruit’ pages.